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Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis

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Additionally, the mechanisms complement each other: as GLP-1 reduces appetite and improves insulin sensitivity, SGLT2 inhibitors independently lower blood glucose through renal elimination, creating a powerful combination that addresses both insulin resistance and glucose overload

Unfortunately, many patients regain weight after discontinuation, so these medications are currently seen as a long-term therapy

What Im not sure about is how much better they are than the other drugs in our arsenal